SCHEMBL2284447

SCHEMBL2284447

O=C1C=CC(=O)N1n1cccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.48
MGLL Q99685 14/20 0.36
GSK3A P49840 2/20 0.36
GSK3B P49841 2/20 0.36
TLR9 Q9NR96 2/20 0.36
FAAH O00519 5/20 0.33
ALDH1A1 P00352 3/20 0.32
LMNA P02545 2/20 0.32
MAPT P10636 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
GMNN O75496 1/20 0.32
THPO P40225 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
HSP90AA1 P07900 2/20 0.31
HPGD P15428 2/20 0.31
XBP1 P17861 2/20 0.31
HTT P42858 2/20 0.31
ALOX12 P18054 1/20 0.31
RUNX1 Q01196 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL157324 0.73 MGLL (0.50) POLBMGLLGSK3AGSK3BTLR9
SCHEMBL31292622 0.65 POLB (0.43) POLBALDH1A1HTT
SCHEMBL28230993 0.61 POLB (0.44) POLBSMN1; SMN2
SCHEMBL11229948 0.60 POLB (0.54) POLBMGLLTLR9
SCHEMBL7997216 0.59 MGLL (0.39) MGLLGSK3AGSK3BTLR9FAAH
SCHEMBL2308600 0.59 ALDH1A1 (0.39) MGLLGSK3AGSK3BTLR9FAAH
SCHEMBL11430716 0.57 MGLL (0.41) MGLLGSK3AGSK3BFAAHALDH1A1
SCHEMBL28076172 0.57 ALDH1A1 (0.40) MGLLGSK3AGSK3BFAAHALDH1A1
SCHEMBL27932529 0.57 POLB (0.32) POLB
SCHEMBL14230817 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109675020-B Oral GLP-1 polypeptide nano preparation and preparation method and application thereof 浙江大学 2021-05-04 CN disclosed
CN-109675020-A A kind of oral GLP-1 polypeptide nanometer formulation and its preparation method and application 浙江大学 2019-04-26 CN disclosed
US-7998726-B2 Method for fixing a protein on a pyrrole-based polymer and use thereof for making a sensor COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2011-08-16 US disclosed
EP-1563304-B1 METHOD FOR FIXING A PROTEIN ON A PYRROLE-BASED POLYMER AND USE THEREOF FOR MAKING A SENSOR COMMISSARIAT ENERGIE ATOMIQUE (FR) 2010-09-15 EP disclosed
US-20060035208-A1 Method for fixing a protein on a pyrrole-based polymer and use thereof for making a sensor COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2006-02-16 US disclosed
EP-1563304-A1 METHOD FOR FIXING A PROTEIN ON A PYRROLE-BASED POLYMER AND USE THEREOF FOR MAKING A SENSOR Commissariat A L'Energie Atomique (FR) 2005-08-17 EP disclosed
WO-2004048972-A1 METHOD FOR FIXING A PROTEIN ON A PYRROLE-BASED POLYMER AND USE THEREOF FOR MAKING A SENSOR COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2004-06-10 WO disclosed
US-4812244-A SULFONATED STYRENE-MALEIMIDE COPOLYMER, SODIUM ACRYLATE-METHACRYLATE COPOLYMER PONY INDUSTRIES, INC. (US) 1989-03-14 US disclosed
US-4797450-A PHENYLMALEIMIDES WITH STYRENE FOLLOWED BY SULFONATION ARCO CHEMICAL COMPANY (US) 1989-01-10 US disclosed
EP-0143508-A2 Additive for water-base drilling fluid and process ATLANTIC RICHFIELD COMPANY (US) 1985-06-05 EP disclosed