SCHEMBL21530752

SCHEMBL21530752

c1ccc(-c2cc(CP(c3ccccc3)c3ccccc3)c(CP(c3ccccc3)c3ccccc3)c(CP(c3ccccc3)c3ccccc3)c2CP(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 1/20 0.32
▸ BACE1 P56817 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21530751 0.84 DPP4 (0.33) DPP4
SCHEMBL6670726 0.77 DPP4 (0.41) DPP4
SCHEMBL28754700 0.76 DPP4 (0.40) DPP4
SCHEMBL29175572 0.76 DPP4 (0.40) DPP4
SCHEMBL28754699 0.76 DPP4 (0.40) DPP4
SCHEMBL8522187 0.76 DPP4 (0.52) DPP4
SCHEMBL14687259 0.73 GPR84 (0.44) —
SCHEMBL19002943 0.71 DPP4 (0.32) DPP4
SCHEMBL29387119 0.70 CYP3A4 (0.43) DPP4
SCHEMBL244078 0.70 CYP3A4 (0.43) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10766833-B2 Hydroformylation method and catalyst using rhodium-ruthenium dual metal and tetradentate phosphine ligand Wuhan Catalys Technology CO., LTD (CN) 2020-09-08 — — US disclosed
US-20190337866-A1 HYDROFORMYLATION METHOD AND CATALYST USING RHODIUM-RUTHENIUM DUAL METAL AND TETRADENTATE PHOSPHINE LIGAND Wuhan Catalys Technology CO., LTD (CN) 2019-11-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190337866-A1 HYDROFORMYLATION METHOD AND CATALYST USING RHODIUM-RUTHENIUM DUAL METAL AND TETRADENTATE PHOSPHINE LIGAND HRH4, PPIP5K2, NUDT1 DPP4 4480/4885BACE1 4762/4885
US-10766833-B2 Hydroformylation method and catalyst using rhodium-ruthenium dual metal and tetradentate phosphine ligand HRH4, PPIP5K2, NUDT1 DPP4 4480/4885BACE1 4762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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