Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | STAT6 | P42226 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30231342 | 0.85 | ACKR3 (0.69) | L3MBTL1ALDH1A1KDM4EACKR3SMN1; SMN2 | |
| SCHEMBL13753140 | 0.83 | L3MBTL1 (0.54) | L3MBTL1POLBALDH1A1HPGDACKR3 | |
| SCHEMBL21210764 | 0.81 | HTT (0.58) | L3MBTL1HPGDLMNATSHRSMN1; SMN2 | |
| SCHEMBL6068233 | 0.80 | CES2 (0.55) | L3MBTL1KDM4EACKR3LMNACYP2C19 | |
| SCHEMBL9363810 | 0.79 | POLB (0.84) | L3MBTL1MCHR1POLBALDH1A1KDM4E | |
| SCHEMBL12438386 | 0.79 | POLB (0.84) | L3MBTL1MCHR1POLBALDH1A1KDM4E | |
| SCHEMBL12462063 | 0.79 | HDAC3 (0.54) | L3MBTL1ACKR3LMNATSHRCYP1A2 | |
| SCHEMBL5636971 | 0.79 | ALPL (0.55) | L3MBTL1ALDH1A1KDM4EACKR3RAB9A | |
| SCHEMBL6544758 | 0.78 | HDAC3 (0.58) | L3MBTL1ALDH1A1HPGDLMNATSHR | |
| SCHEMBL7967927 | 0.78 | NPC1 (0.50) | L3MBTL1POLBKDM4EHPGDACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11504439-B2 | Radioactive compound for diagnosis of malignant melanoma and use thereof | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2022-11-22 | — | — | US | disclosed |
| EP-3816156-A1 | RADIOACTIVE COMPOUND FOR TREATMENT OF MELANOMA AND USE THEREOF | Industry Foundation of Chonnam National University (KR) | 2021-05-05 | — | — | EP | disclosed |
| US-20210113719-A1 | RADIOACTIVE COMPOUND FOR TREATMENT OF MELANOMA AND USE THEREOF | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2021-04-22 | — | — | US | disclosed |
| EP-3569589-A1 | RADIOACTIVE COMPOUND FOR DIAGNOSIS OF MALIGNANT MELANOMA AND USE THEREOF | Industry Foundation of Chonnam National University (KR) | 2019-11-20 | — | — | EP | disclosed |
| US-20190336621-A1 | RADIOACTIVE COMPOUND FOR DIAGNOSIS OF MALIGNANT MELANOMA AND USE THEREOF | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2019-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210113719-A1 | RADIOACTIVE COMPOUND FOR TREATMENT OF MELANOMA AND USE THEREOF | CD47, TYR, NRAS | L3MBTL1 1971/4885MCHR1 128/4885POLB 2043/4885 |
| US-20190336621-A1 | RADIOACTIVE COMPOUND FOR DIAGNOSIS OF MALIGNANT MELANOMA AND USE THEREOF | MITF, BRAF, MEN1 | L3MBTL1 943/4885MCHR1 66/4885POLB 3939/4885 |
| US-11504439-B2 | Radioactive compound for diagnosis of malignant melanoma and use thereof | MITF, BRAF, MEN1 | L3MBTL1 943/4885MCHR1 66/4885POLB 3939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.