SCHEMBL21531540

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25457369	0.92	DRD4 (0.38)	KDM4EALDH1A1CA12CA9PGR
	SCHEMBL10196956	0.89	ABCB1 (0.38)	ALDH1A1ABCB1
	SCHEMBL12293879	0.87	ABCB1 (0.42)	KDM4EALDH1A1ABCB1
	SCHEMBL64690	0.87	ABCB1 (0.42)	KDM4EALDH1A1ABCB1
	SCHEMBL954434	0.86	ABCB1 (0.41)	KDM4EALDH1A1ABCB1
	SCHEMBL21531521	0.86	CA12 (0.45)	KDM4EALDH1A1CA12CA9PGR
	SCHEMBL2680751	0.85	ABCB1 (0.40)	KDM4EALDH1A1ABCB1
	SCHEMBL10196910	0.85	PARP1 (0.38)	ALDH1A1ABCB1
	SCHEMBL20841749	0.83	ABCB1 (0.39)	ALDH1A1ABCB1
	SCHEMBL20841761	0.83	ABCB1 (0.39)	ALDH1A1POLBABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.