Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21531658 | 0.89 | NPSR1 (0.44) | NPSR1ALDH1A1GPBAR1LMNACYP2C9 | |
| SCHEMBL21531660 | 0.79 | PDE4B (0.47) | ALDH1A1LMNACYP2C9MAPK1KMT2A | |
| SCHEMBL27415402 | 0.73 | ALDH1A1 (0.46) | NPSR1ALDH1A1GPBAR1LMNACYP2C9 | |
| SCHEMBL27415403 | 0.73 | ALDH1A1 (0.46) | NPSR1ALDH1A1GPBAR1LMNACYP2C9 | |
| SCHEMBL6768435 | 0.73 | NPSR1 (0.57) | NPSR1ALDH1A1LMNACYP2C19MAPK1 | |
| SCHEMBL8744093 | 0.71 | ALDH1A1 (0.60) | NPSR1ALDH1A1LMNAPOLB | |
| SCHEMBL16065869 | 0.66 | HTT (0.47) | NPSR1ALDH1A1GPBAR1LMNACYP2C9 | |
| SCHEMBL9745628 | 0.66 | ALDH1A1 (0.59) | NPSR1ALDH1A1LMNAMAPT | |
| SCHEMBL9745453 | 0.66 | ALDH1A1 (0.59) | NPSR1ALDH1A1LMNAMAPT | |
| SCHEMBL9745446 | 0.66 | ALDH1A1 (0.59) | NPSR1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190337955-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | UNIV NANYANG TECH (SG) | 2019-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190337955-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | CBR1, CBR3, CAT | NPSR1 3264/4885ALDH1A1 96/4885GPBAR1 1658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.