SCHEMBL21532298

SCHEMBL21532298

c1ccc(-c2nnc(-c3ccccc3)n2-c2cccc3c2c2ccccc2n3-c2cccc(-c3cccc(-n4c5ccccc5c5ccc6c7ccccc7oc6c54)c3)c2)cc1

nearest known ligand 0.32

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
GAA P10253 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HIF1A Q16665 1/20 0.31
ALDH1A1 P00352 2/20 0.30
POLB P06746 1/20 0.30
TSHR P16473 1/20 0.30
BRCA1 P38398 1/20 0.30
HSD17B10 Q99714 1/20 0.30
LMNA P02545 1/20 0.30
PPARG P37231 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
NR2E3 Q9Y5X4 1/20 0.30
NCOR2 Q9Y618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21532718 0.97 OPRD1 (0.32) OPRD1KDM4EATML3MBTL1MEN1
SCHEMBL21532533 0.94 ALOX5 (0.34) OPRD1KDM4EATML3MBTL1MEN1
SCHEMBL21532536 0.92 MEN1 (0.32) OPRD1KDM4EATML3MBTL1MEN1
SCHEMBL21532279 0.91 ALDH1A1 (0.34) OPRD1KDM4EATML3MBTL1MEN1
SCHEMBL21532570 0.91 OPRD1 (0.32) OPRD1KDM4EATML3MBTL1MEN1
SCHEMBL21532303 0.90 ALDH1A1 (0.33) OPRD1KDM4EATML3MBTL1MEN1
SCHEMBL21532424 0.90 SMN1; SMN2 (0.34) KDM4EMEN1KMT2ASMN1; SMN2HIF1A
SCHEMBL21532713 0.89 OPRD1 (0.34) OPRD1KDM4EATML3MBTL1MEN1
SCHEMBL21532258 0.89 ALOX5 (0.35) OPRD1KDM4EATML3MBTL1MEN1
SCHEMBL21532295 0.88 ALDH1A1 (0.36) OPRD1KDM4EATML3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11145825-B2 Condensed cyclic compound and organic light-emitting device including i he same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-10-12 US disclosed
US-20190334095-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11145825-B2 Condensed cyclic compound and organic light-emitting device including i he same CRY1, CCNT1, CCNA1 OPRD1 417/4885KDM4E 4144/4885ATM 622/4885
US-20190334095-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNT1, ARL1 OPRD1 463/4885KDM4E 3893/4885ATM 368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.