Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 3/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 1.00 |
| ▸ | HTT | P42858 | 3/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.77 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168699 | 0.95 | ALDH1A1 (0.90) | ALDH1A1ALOX12NPSR1HTTL3MBTL1 | |
| SCHEMBL167636 | 0.87 | ALDH1A1 (0.77) | ALDH1A1ALOX12NPSR1HTTL3MBTL1 | |
| SCHEMBL2153304 | 0.85 | ALDH1A1 (0.74) | ALDH1A1ALOX12NPSR1HTTL3MBTL1 | |
| SCHEMBL12467306 | 0.84 | ALDH1A1 (0.72) | ALDH1A1ALOX12NPSR1HTTL3MBTL1 | |
| SCHEMBL165611 | 0.84 | ALDH1A1 (0.72) | ALDH1A1ALOX12NPSR1HTTL3MBTL1 | |
| SCHEMBL2153021 | 0.82 | ALDH1A1 (0.70) | ALDH1A1ALOX12NPSR1HTTL3MBTL1 | |
| SCHEMBL168012 | 0.82 | ALDH1A1 (0.69) | ALDH1A1ALOX12NPSR1HTTL3MBTL1 | |
| SCHEMBL168734 | 0.82 | ALDH1A1 (0.69) | ALDH1A1ALOX12NPSR1HTTL3MBTL1 | |
| SCHEMBL12839889 | 0.81 | ALDH1A1 (0.68) | ALDH1A1ALOX12NPSR1HTTL3MBTL1 | |
| SCHEMBL167878 | 0.81 | ALDH1A1 (0.67) | ALDH1A1ALOX12NPSR1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295890-A1 | GLYCOSAMINOGLYCAN INHIBITORS | Zacharon Pharmaceutical, Inc. (US) | 2012-11-22 | — | — | US | disclosed |
| WO-2011082175-A2 | GLYCOSAMINOGLYCAN INHIBITORS | ZACHARON PHARMACEUTICALS, INC. (US) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295890-A1 | GLYCOSAMINOGLYCAN INHIBITORS | CSGALNACT1, FUT5, ST3GAL3 | ALDH1A1 797/4885ALOX12 3731/4885NPSR1 574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.