Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.90 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.90 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.90 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.90 |
| ▸ | HTT | P42858 | 3/20 | 0.90 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.90 |
| ▸ | MEN1 | O00255 | 1/20 | 0.90 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.90 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.90 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CCR6 | P51684 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2153243 | 0.95 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1ALOX12NPSR1HTT | |
| SCHEMBL12467306 | 0.89 | ALDH1A1 (0.72) | ALDH1A1L3MBTL1ALOX12NPSR1HTT | |
| SCHEMBL165611 | 0.89 | ALDH1A1 (0.72) | ALDH1A1L3MBTL1ALOX12NPSR1HTT | |
| SCHEMBL167636 | 0.87 | ALDH1A1 (0.77) | ALDH1A1L3MBTL1ALOX12NPSR1HTT | |
| SCHEMBL168734 | 0.87 | ALDH1A1 (0.69) | ALDH1A1L3MBTL1ALOX12NPSR1HTT | |
| SCHEMBL167878 | 0.86 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1ALOX12NPSR1HTT | |
| SCHEMBL256654 | 0.86 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1ALOX12NPSR1HTT | |
| SCHEMBL168039 | 0.86 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1ALOX12NPSR1HTT | |
| SCHEMBL168012 | 0.85 | ALDH1A1 (0.69) | ALDH1A1L3MBTL1ALOX12NPSR1HTT | |
| SCHEMBL166925 | 0.83 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1ALOX12NPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180170863-A1 | ROR GAMMA (RORY) MODULATORS | LEAD PHARMA HOLDING B.V. (NL) | 2018-06-21 | — | — | US | disclosed |
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180170863-A1 | ROR GAMMA (RORY) MODULATORS | RORB, RORA, RORC | ALDH1A1 687/4885L3MBTL1 2209/4885ALOX12 2633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.