Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.60 |
| ▸ | GRM6 | O15303 | 1/20 | 0.60 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.60 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.60 |
| ▸ | GSR | P00390 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.60 |
| ▸ | GRM5 | P41594 | 1/20 | 0.60 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.60 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.60 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.60 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.60 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.60 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.60 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.60 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.60 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.60 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.60 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.60 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19525766 | 0.82 | GRM8 (0.60) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL6413584 | 0.78 | GRM8 (0.56) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL4459586 | 0.77 | GRM8 (0.54) | GRM8GRM6GRIN2DGRIN3BGSR | |
| D-Glutamate SCHEMBL1332297 | 0.75 | GRM8 (1.00) | GRM8GRM6GRIN2DGRIN3BGSR | |
| D-Glutamate SCHEMBL17127348 | 0.75 | GRM8 (1.00) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL25384088 | 0.75 | CYP1A2 (0.71) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Glutamic Acid SCHEMBL5704264 | 0.75 | GRM8 (1.00) | GRM8GRM6GRIN2DGRIN3BGSR | |
| D-Glutamate SCHEMBL1330824 | 0.75 | GRM8 (1.00) | GRM8GRM6GRIN2DGRIN3BGSR | |
| D-Glutamate SCHEMBL1330484 | 0.75 | GRM8 (1.00) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Glutamic Acid SCHEMBL248800 | 0.75 | GRM8 (1.00) | GRM8GRM6GRIN2DGRIN3BGSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228076-B1 | A SUBSTANTIALLY CELL MEMBRANE IMPERMEABLE COMPOUND AND USE THEREOF | NEWSOUTH INNOVATIONS PTY LTD (AU) | 2011-07-06 | — | — | EP | disclosed |
| US-7674775-B2 | Substantially cell membrane impermeable compound and use thereof | NEW SOUTH INNOVATIONS PTY LIMITED (AU) | 2010-03-09 | — | — | US | disclosed |
| US-7498406-B2 | Substantially cell membrane impermeable compound and use thereof | NEW SOUTH INNOVATIONS PTY LIMITED (AU) | 2009-03-03 | — | — | US | disclosed |
| US-7186695-B2 | Treatment of arthritis with arsenoxide compounds | NEW SOUTH INNOVATIONS PTY LIMITED (AU) | 2007-03-06 | — | — | US | disclosed |
| US-20070037995-A1 | 4-(N (S-glutathionylacetyl)amino)phenylarsenoxide (GSAO) and derivatives; antiinflammatory and antitumor agents; blood and autoimmune disorders; viral infections; anticoagulants | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2007-02-15 | — | — | US | disclosed |
| US-7074766-B1 | Substantially cell membrane impermeable compound and use thereof | NEW SOUTH INNOVATIONS PTY LIMITED (AU) | 2006-07-11 | — | — | US | disclosed |
| EP-1379233-A4 | USE OF A SUBSTANTIALLY CELL MEMBRANE IMPERMEABLE COMPOUND FOR TREATING ARTHRITIS | UNISEARCH LTD (AU) | 2005-10-26 | — | — | EP | disclosed |
| US-20040138102-A1 | Use of a substantially cell membrane impermeable compound for treating arthritis | NEW SOUTH INNOVATIONS PTY LIMITED (AU) | 2004-07-15 | — | — | US | disclosed |
| EP-1379233-A1 | USE OF A SUBSTANTIALLY CELL MEMBRANE IMPERMEABLE COMPOUND FOR TREATING ARTHRITIS | UNISEARCH LIMITED (AU) | 2004-01-14 | — | — | EP | disclosed |
| WO-2003003011-A1 | MODIFICATION OF ANGIOGENESIS BY TARGETING PROTEIN TYROSINE PHOSPHATASES | UNISEARCH LIMITED (AU) | 2003-01-09 | — | — | WO | disclosed |
| EP-1228076-A4 | A SUBSTANTIALLY CELL MEMBRANE IMPERMEABLE COMPOUND AND USE THEREOF | UNISEARCH LTD (AU) | 2002-11-06 | — | — | EP | disclosed |
| WO-2002074305-A1 | USE OF A SUBSTANTIALLY CELL MEMBRANE IMPERMEABLE COMPOUND FOR TREATING ARTHRITIS | UNISEARCH LIMITED (AU) | 2002-09-26 | — | — | WO | disclosed |
| EP-1228076-A1 | A SUBSTANTIALLY CELL MEMBRANE IMPERMEABLE COMPOUND AND USE THEREOF | UNISEARCH LIMITED (AU) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001021628-A1 | A SUBSTANTIALLY CELL MEMBRANE IMPERMEABLE COMPOUND AND USE THEREOF | UNISEARCH LIMITED (AU) | 2001-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037995-A1 | 4-(N (S-glutathionylacetyl)amino)phenylarsenoxide (GSAO) and derivatives; antiinflammatory and antitumor agents; blood and autoimmune disorders; viral infections; anticoagulants | QSOX1, GSS, SSB | GRM8 1978/4885GRM6 2134/4885GRIN2D 2533/4885 |
| US-20040138102-A1 | Use of a substantially cell membrane impermeable compound for treating arthritis | CD47, SLC7A1, SLC26A3 | GRM8 3016/4885GRM6 2933/4885GRIN2D 4356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.