Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.71 |
| ▸ | RAB9A | P51151 | 6/20 | 0.71 |
| ▸ | CASP3 | P42574 | 1/20 | 0.71 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.71 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.71 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.71 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19206635 | 0.90 | MAPT (0.61) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL21532953 | 0.89 | RAB9A (0.56) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL21532931 | 0.87 | RAB9A (0.57) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL19240119 | 0.84 | PNLIP (0.54) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL21532952 | 0.81 | NPC1 (0.55) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL19206631 | 0.81 | PARP1 (0.59) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL19206640 | 0.81 | PARP1 (0.55) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL19206639 | 0.79 | PARP1 (0.56) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL27772010 | 0.78 | PARP1 (0.72) | RAB9APARP1MAPTGAATP53 | |
| SCHEMBL19206641 | 0.78 | CD38 (0.58) | NPC1RAB9ACASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730839-B2 | Quinolines as cytoprotective agents | NEURODON CORPORATION | 2020-08-04 | — | — | US | disclosed |
| US-20190330156-A1 | QUINOLINES AS CYTOPROTECTIVE AGENTS | NEURODON CORPORATION | 2019-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10730839-B2 | Quinolines as cytoprotective agents | IAPP, NFE2L2, NLN | NPC1 316/4885RAB9A 1744/4885CASP3 207/4885 |
| US-20190330156-A1 | QUINOLINES AS CYTOPROTECTIVE AGENTS | IAPP, NFE2L2, NLN | NPC1 316/4885RAB9A 1744/4885CASP3 207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.