Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | ALDH1A2 | O94788 | 5/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 5/20 | 0.36 |
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29303864 | 0.85 | ALDH1A2 (0.37) | ALDH1A1ALDH1A2ALDH1A3ELANEMPO | |
| SCHEMBL29303858 | 0.83 | ALDH1A2 (0.36) | ALDH1A1ALDH1A2ALDH1A3KDM5A | |
| SCHEMBL29304924 | 0.81 | ALDH1A1 (0.39) | ALDH1A1ALDH1A2ALDH1A3MPOKDM5A | |
| SCHEMBL29303422 | 0.78 | HDAC8 (0.34) | ALDH1A1ALDH1A2ALDH1A3MPOPTPN11 | |
| SCHEMBL21536089 | 0.77 | ALDH1A2 (0.39) | ALDH1A1ALDH1A2ALDH1A3ELANEMPO | |
| SCHEMBL17680609 | 0.72 | USP7 (0.41) | ALDH1A1ELANEBRD4CREBBPGABRA1 | |
| SCHEMBL29303756 | 0.70 | KDM5A (0.38) | ALDH1A1ALDH1A2ALDH1A3MPOKDM5A | |
| SCHEMBL29303239 | 0.68 | KDM5A (0.38) | ALDH1A1ALDH1A2ALDH1A3KDM5A | |
| SCHEMBL29304475 | 0.68 | CHRM1 (0.36) | ALDH1A1ALDH1A2ALDH1A3KDM5A | |
| SCHEMBL29304342 | 0.68 | GABRA1 (0.34) | ELANEMPOGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10919885-B2 | Compounds and uses thereof | YUMANITY THERAPEUTICS, INC. (US) | 2021-02-16 | — | — | US | disclosed |
| US-20190330198-A1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2019-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10919885-B2 | Compounds and uses thereof | NLN, ACHE, CLN6 | ALDH1A1 656/4885ALDH1A2 138/4885ALDH1A3 379/4885 |
| US-20190330198-A1 | COMPOUNDS AND USES THEREOF | NLN, ACHE, CLN6 | ALDH1A1 656/4885ALDH1A2 138/4885ALDH1A3 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.