Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.60 |
| ▸ | SCD5 | Q86SK9 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | SCD | O00767 | 1/20 | 0.58 |
| ▸ | PLK1 | P53350 | 1/20 | 0.52 |
| ▸ | CDH1 | P12830 | 1/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.52 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.52 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | RARG | P13631 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10153708 | 0.80 | ALDH1A1 (0.67) | ALDH1A1HPGDMAPTNPC1RAB9A | |
| SCHEMBL892878 | 0.79 | ALDH1A1 (0.72) | ALDH1A1PTPN1HPGDMAPTRECQL | |
| SCHEMBL11902392 | 0.79 | ALDH1A1 (0.62) | ALDH1A1PTPN1HPGDMAPTRECQL | |
| SCHEMBL11961394 | 0.78 | NPC1 (0.60) | SCD5HPGDMAPTSCDPLK1 | |
| SCHEMBL4093700 | 0.78 | ALDH1A1 (0.66) | ALDH1A1PTPN1HPGDMAPTRECQL | |
| SCHEMBL6802996 | 0.78 | TP53 (0.68) | ALDH1A1HPGDMAPTROCK2PIM1 | |
| SCHEMBL17286672 | 0.77 | NPC1 (0.58) | SCD5MAPTSCDPLK1NPC1 | |
| SCHEMBL72786 | 0.77 | ALDH1A1 (1.00) | ALDH1A1PTPN1HPGDMAPTRECQL | |
| SCHEMBL3219488 | 0.77 | RAB9A (0.72) | ALDH1A1PTPN1MAPTROCK2PIM1 | |
| SCHEMBL71299 | 0.77 | ALDH1A1 (1.00) | ALDH1A1PTPN1HPGDMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10919885-B2 | Compounds and uses thereof | YUMANITY THERAPEUTICS, INC. (US) | 2021-02-16 | — | — | US | disclosed |
| US-20190330198-A1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2019-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10919885-B2 | Compounds and uses thereof | NLN, ACHE, CLN6 | ALDH1A1 656/4885PTPN1 4301/4885SCD5 1575/4885 |
| US-20190330198-A1 | COMPOUNDS AND USES THEREOF | NLN, ACHE, CLN6 | ALDH1A1 656/4885PTPN1 4301/4885SCD5 1575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.