Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 7/20 | 0.66 |
| ▸ | RAB9A | P51151 | 7/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.62 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3219488 | 0.86 | RAB9A (0.72) | TP53NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL10153708 | 0.85 | ALDH1A1 (0.67) | NPC1RAB9AALDH1A1KMT2AHPGD | |
| SCHEMBL21446983 | 0.84 | ROCK2 (0.59) | TP53NPC1RAB9AALDH1A1MLLT1 | |
| SCHEMBL22322454 | 0.84 | HPGD (0.55) | TP53NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL15196594 | 0.81 | ALDH1A1 (0.72) | TP53NPC1RAB9AALDH1A1HDAC3 | |
| SCHEMBL19245571 | 0.80 | ROCK2 (0.57) | TP53NPC1RAB9AALDH1A1HDAC6 | |
| SCHEMBL72786 | 0.80 | ALDH1A1 (1.00) | TP53NPC1RAB9AALDH1A1HDAC3 | |
| SCHEMBL21536740 | 0.78 | ALDH1A1 (0.62) | TP53NPC1RAB9AALDH1A1HDAC4 | |
| SCHEMBL17732022 | 0.78 | ALDH1A1 (0.72) | TP53NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL3236082 | 0.78 | ROCK2 (0.49) | TP53NPC1RAB9AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |