Sugi Predict

Sugi Predict / Compounds / SCHEMBL21545839

SCHEMBL21545839

SCHEMBL21545839

Cc1cn([C@H]2C[C@H](O)[C@@H](CO[Si](C)(C)C(C)(C)C)O2)c(=O)n(C(=O)c2ccccc2)c1=O

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ TOP2A P11388 6/20 0.43
▸ RNASE1 P07998 1/20 0.39
▸ TYMS P04818 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21563858 1.00 TOP2A (0.43) TOP2ARNASE1TYMS
SCHEMBL21563857 0.90 TOP2A (0.42) TOP2ARNASE1
SCHEMBL14024393 0.86 TYMP (0.38) TOP2ATYMS
SCHEMBL4730469 0.85 ALDH1A1 (0.46) RNASE1TYMS
SCHEMBL26233449 0.85 RNASE1 (0.42) RNASE1
SCHEMBL30586112 0.85 TK1 (0.41) TOP2ARNASE1
SCHEMBL21563855 0.84 RNASE1 (0.48) RNASE1
SCHEMBL9443821 0.84 RNASE1 (0.48) RNASE1
SCHEMBL537189 0.84 RNASE1 (0.48) RNASE1
SCHEMBL21563863 0.83 TOP2A (0.47) TOP2ATYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230264164-A1 HOMOPOLYMER ENCODED NUCLEIC ACID MEMORY TRILINK BIOTECHNOLOGIES, LLC 2023-08-24 — — US disclosed
US-11612873-B2 Homopolymer encoded nucleic acid memory Molecular Assemblies, Inc. (US) 2023-03-28 — — US disclosed
WO-2020219853-A1 HOMOPOLYMER ENCODED NUCLEIC ACID MEMORY Molecular Assemblies, Inc. (US) 2020-10-29 — — WO disclosed
US-20190344239-A1 HOMOPOLYMER ENCODED NUCLEIC ACID MEMORY Molecular Assemblies, Inc. 2019-11-14 — — US disclosed