SCHEMBL21546480

SCHEMBL21546480

Cc1ccc(-c2ccc3c4ccccc4n(-c4cc(C#N)cc(-n5c6ccccc6c6ccc(-c7ccc(C)cc7C)cc65)c4-c4cccc(C#N)c4)c3c2)c(C)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.35
PRF1 P14222 1/20 0.32
BRD4 O60885 1/20 0.32
CHEK1 O14757 1/20 0.32
ADRA2C P18825 1/20 0.32
PDE9A O76083 1/20 0.32
PDE1C Q14123 1/20 0.32
PGR P06401 3/20 0.32
ALDH1A3 P47895 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2B Q13224 1/20 0.32
CYP1A2 P05177 3/20 0.32
CYP3A4 P08684 3/20 0.32
CYP2C19 P33261 3/20 0.32
CYP2D6 P10635 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 2/20 0.31
ALDH1A1 P00352 2/20 0.31
KMT2A Q03164 2/20 0.31
CLK4 Q9HAZ1 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21546985 0.96 ELANE (0.35) ELANEPRF1BRD4CHEK1ADRA2C
SCHEMBL21546947 0.95 ELANE (0.36) ELANEPRF1BRD4CHEK1ADRA2C
SCHEMBL21414104 0.93 PDE9A (0.35) PDE9APDE1CLMNA
SCHEMBL21928372 0.91 CYP1A2 (0.36) ELANECHEK1ALDH1A3GRIN1GRIN2B
SCHEMBL22761032 0.91 PGR (0.31) ELANEPGR
SCHEMBL21546687 0.91 ADRA2C (0.36) ELANEBRD4ADRA2CPGRCYP1A2
SCHEMBL21547104 0.91 MAT2A (0.36) ELANEPRF1GRIN1GRIN2BAR
SCHEMBL21546982 0.91 ELANE (0.36) ELANEPRF1BRD4CHEK1ADRA2C
SCHEMBL21547093 0.90 ELANE (0.36) ELANEPRF1BRD4CHEK1ADRA2C
SCHEMBL21546619 0.90 ALDH1A3 (0.34) ELANECHEK1PDE9APDE1CPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3478793-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-11-06 EP disclosed