Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21546619 | 0.96 | ALDH1A3 (0.34) | TGFBR1CLK4ALDH1A3GRIA2GRIA4 | |
| SCHEMBL21546733 | 0.92 | PGR (0.36) | TGFBR1CLK4ALDH1A3GRIA2GRIA4 | |
| SCHEMBL21414264 | 0.91 | CHEK1 (0.33) | ALDH1A1CHEK1 | |
| SCHEMBL21546984 | 0.91 | GRM5 (0.37) | TGFBR1CLK4ALDH1A3GRIA2GRIA4 | |
| SCHEMBL21546948 | 0.90 | PTGER4 (0.37) | TGFBR1CLK4ALDH1A3GRIA2GRIA4 | |
| SCHEMBL21931708 | 0.90 | IDO1 (0.36) | TGFBR1CLK4ALDH1A3IDO1ALDH1A1 | |
| SCHEMBL21546479 | 0.89 | GRIA2 (0.39) | TGFBR1CLK4ALDH1A3GRIA2GRIA4 | |
| SCHEMBL21546985 | 0.89 | ELANE (0.35) | TGFBR1ALDH1A3GRIA2GRIA4PGR | |
| SCHEMBL21546746 | 0.89 | MAP4K4 (0.40) | CLK4ALDH1A3GRIA2GRIA4PGR | |
| SCHEMBL23348415 | 0.88 | ALDH1A1 (0.34) | ALDH1A1CYP1A2ARCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3478793-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-11-06 | — | — | EP | disclosed |