SCHEMBL2154803

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21055792	0.85	APP (0.48)	CYP1A2CYP3A4CYP2C19CLK4LMNA
	SCHEMBL14474124	0.80	CYP1A2 (0.62)	CYP1A2CYP3A4CYP2C19CLK4LMNA
	SCHEMBL2155882	0.80	CYP1A2 (0.65)	CYP1A2CYP3A4CYP2C19CLK4LMNA
	SCHEMBL2154983	0.79	ABCG2 (0.65)	CYP1A2CYP3A4CYP2C19CLK4LMNA
	SCHEMBL8898174	0.78	TRIM58 (0.56)	CYP1A2CYP3A4CYP2C19CLK4LMNA
	SCHEMBL16183454	0.78	TRIM58 (0.53)	CYP1A2CYP3A4CYP2C19CLK4LMNA
	SCHEMBL14474065	0.78	LMNA (0.63)	CYP1A2CYP3A4CYP2C19CLK4LMNA
	SCHEMBL14475201	0.78	CYP1A2 (0.63)	CYP1A2CYP3A4CYP2C19CLK4LMNA
	SCHEMBL17212414	0.77	SYK (0.66)	CYP1A2CYP3A4CYP2C19CLK4LMNA
	SCHEMBL2154624	0.76	CYP1A2 (0.60)	CYP1A2CYP3A4CYP2C19CLK4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.