Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GGT1 | P19440 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.32 |
| ▸ | CPB1 | P15086 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL853631 | 0.82 | GGT1 (0.38) | GGT1CPB2TDP1CA1CA2 | |
| SCHEMBL853630 | 0.82 | GGT1 (0.38) | GGT1CPB2TDP1CA1CA2 | |
| SCHEMBL16382140 | 0.77 | GGT1 (0.41) | GGT1HSD17B10CPB2CPB1 | |
| SCHEMBL16086279 | 0.74 | LMNA (0.39) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL21548085 | 0.72 | LMNA (0.47) | LMNA | |
| SCHEMBL7365479 | 0.71 | CTSK (0.39) | TDP1CA1CA2 | |
| SCHEMBL27926587 | 0.71 | CTSK (0.39) | TDP1CA1CA2 | |
| SCHEMBL16426525 | 0.70 | GGT1 (0.39) | GGT1CPB2CPB1TDP1CA1 | |
| SCHEMBL16086302 | 0.70 | TSHR (0.31) | LMNATSHRCYP3A4NFKB1ADRA1A | |
| SCHEMBL28796948 | 0.70 | CYP3A4 (0.49) | LMNAHSD17B10TSHRCYP3A4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564240-A1 | PIPERIDINE INTERMEDIATES | Purdue Pharma L.P. (US) | 2019-11-06 | — | — | EP | disclosed |