Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 2/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | CFD | P00746 | 9/20 | 0.37 |
| ▸ | CSF1R | P07333 | 2/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20356518 | 0.91 | KMO (0.39) | CD38GRM4ALDH1A1KMT2AATM | |
| Hydrochloric Acid SCHEMBL21526103 | 0.90 | KMO (0.38) | CD38GRM4ALDH1A1KMT2AATM | |
| SCHEMBL21548886 | 0.82 | GRM4 (0.35) | GRM4ALDH1A1KMT2AATML3MBTL1 | |
| SCHEMBL21526043 | 0.80 | GAA (0.39) | ALDH1A1KMT2AATML3MBTL1MAPK8 | |
| SCHEMBL20356519 | 0.79 | MAPK8 (0.38) | ALDH1A1L3MBTL1MAPK8MAPK9 | |
| Hydrochloric Acid SCHEMBL21526076 | 0.78 | MAPK8 (0.38) | ALDH1A1KMT2AL3MBTL1MAPK8MAPK9 | |
| SCHEMBL20356522 | 0.78 | ALDH1A1 (0.38) | ALDH1A1KMT2AATML3MBTL1JAK3 | |
| Hydrochloric Acid SCHEMBL21526057 | 0.77 | ALDH1A1 (0.37) | ALDH1A1KMT2AATML3MBTL1JAK3 | |
| SCHEMBL20356521 | 0.75 | LMNA (0.42) | ALDH1A1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL21526086 | 0.74 | LMNA (0.42) | ALDH1A1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564216-A1 | PYRIMIDINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2019-11-06 | — | — | EP | disclosed |