Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CCR4 | P51679 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21548857 | 0.86 | KMT2A (0.34) | L3MBTL1ALDH1A1KMT2AATMGRM5 | |
| SCHEMBL20356518 | 0.83 | KMO (0.39) | GRM4L3MBTL1ALDH1A1KMT2AATM | |
| SCHEMBL21548814 | 0.83 | LMNA (0.39) | L3MBTL1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21548885 | 0.82 | CD38 (0.39) | GRM4L3MBTL1ALDH1A1KMT2AMPO | |
| Hydrochloric Acid SCHEMBL21526103 | 0.82 | KMO (0.38) | GRM4L3MBTL1ALDH1A1KMT2AATM | |
| SCHEMBL21548856 | 0.81 | HTT (0.40) | ALDH1A1KMT2AP2RX7MEN1SMN1; SMN2 | |
| SCHEMBL21526068 | 0.75 | PTPN11 (0.36) | L3MBTL1ALDH1A1KMT2AATMP2RX7 | |
| SCHEMBL21548940 | 0.75 | CCR4 (0.35) | L3MBTL1ALDH1A1KMT2AMEN1CCR4 | |
| SCHEMBL21526043 | 0.74 | GAA (0.39) | L3MBTL1ALDH1A1KMT2AATMGAA | |
| SCHEMBL21526129 | 0.72 | GAA (0.33) | L3MBTL1ALDH1A1KMT2AATMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564216-B1 | PYRIMIDINE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2021-10-27 | — | — | EP | disclosed |
| EP-3564216-A1 | PYRIMIDINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2019-11-06 | — | — | EP | disclosed |