SCHEMBL2155007

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14475857	0.85	ADORA3 (0.53)	CYP1A2MAPTCYP3A4CYP2D6CYP2C9
	SCHEMBL2154895	0.84	CYP1A2 (0.71)	CYP1A2MAPTKMT2ACYP3A4MEN1
	SCHEMBL14727730	0.81	MEN1 (0.55)	CYP1A2MAPTKMT2ACYP3A4MEN1
	SCHEMBL14475879	0.80	WNT1 (0.48)	CYP1A2MAPTKMT2ACYP3A4MEN1
	SCHEMBL2155823	0.80	KMT2A (0.52)	CYP1A2MAPTKMT2ACYP3A4MEN1
	SCHEMBL2155318	0.79	KMT2A (0.55)	CYP1A2MAPTKMT2ACYP3A4MEN1
	SCHEMBL14475416	0.78	RXFP1 (0.61)	CYP1A2MAPTKMT2ACYP3A4MEN1
	SCHEMBL7277316	0.77	PDE5A (0.70)	CYP1A2MAPTKMT2ACYP3A4MEN1
	SCHEMBL7285873	0.77	PDE5A (0.78)	CYP1A2MAPTKMT2ACYP3A4MEN1
	SCHEMBL14727594	0.76	GBA1 (0.59)	CYP1A2KMT2ACYP3A4MEN1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.