Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14817523 | 0.81 | LMNA (0.42) | LMNAL3MBTL1HTTPLAUKMT2A | |
| SCHEMBL23920415 | 0.80 | FAAH (0.36) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL25630960 | 0.72 | FAAH (0.45) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL14217912 | 0.69 | FAAH (0.50) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL319608 | 0.67 | KMT2A (0.46) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL23438276 | 0.67 | FAAH (0.44) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL194085 | 0.67 | HTT (0.46) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL10438892 | 0.66 | KMT2A (0.44) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL23991849 | 0.66 | FAAH (0.47) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL14535097 | 0.66 | FAAH (0.47) | FAAHPHGDHMGLLCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3563848-A1 | SERPIN INHIBITORS FOR THE TREATMENT OF PRION AND PRION-LIKE DISEASES | S.I.S.S.A. Scuola Internazionale Superiore di Studi Avanzati (IT) | 2019-11-06 | — | — | EP | disclosed |