Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21554017 | 0.80 | FAAH (0.37) | FAAHPHGDHMGLLSIGMAR1CA12 | |
| SCHEMBL14817523 | 0.72 | LMNA (0.42) | LMNAL3MBTL1KMT2AMEN1NPC1 | |
| SCHEMBL28752878 | 0.70 | TP53 (0.46) | TP53LMNAL3MBTL1KMT2AMEN1 | |
| SCHEMBL24426151 | 0.70 | TP53 (0.39) | FAAHPHGDHMGLLTP53CA12 | |
| SCHEMBL25630960 | 0.67 | FAAH (0.45) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL12411241 | 0.66 | TP53 (0.44) | FAAHPHGDHMGLLTP53SIGMAR1 | |
| SCHEMBL3399855 | 0.64 | TP53 (0.65) | TP53LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL14817479 | 0.63 | MTNR1A (0.41) | LMNAL3MBTL1KMT2AMEN1NPC1 | |
| SCHEMBL20471127 | 0.63 | TP53 (0.41) | FAAHPHGDHMGLLTP53SIGMAR1 | |
| SCHEMBL23954324 | 0.62 | TP53 (0.47) | TP53L3MBTL1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892623-A1 | COMPOUNDS HAVING PDE9A INHIBITORY ACTIVITY, AND PHARMACEUTICAL USES THEREOF | Korea Research Institute of Chemical Technology (KR) | 2021-10-13 | — | — | EP | disclosed |