Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 8/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21557568 | 0.86 | ABL1 (0.42) | LTB4RABL1CNR1 | |
| SCHEMBL21557499 | 0.75 | MAP4K4 (0.50) | ABL1DHODHKAT6A | |
| SCHEMBL21557666 | 0.75 | CYP4F2 (0.47) | ABL1DHODH | |
| SCHEMBL21557622 | 0.73 | F2 (0.47) | ABL1DHODHKAT6A | |
| SCHEMBL23362454 | 0.72 | GSK3B (0.39) | LTB4RABL1KAT6AACVR1BTGFBR1 | |
| SCHEMBL2794624 | 0.72 | GLS (0.47) | LTB4RLTB4R2 | |
| SCHEMBL28073801 | 0.71 | CYP3A4 (0.44) | FFAR1 | |
| SCHEMBL21557486 | 0.71 | FFAR1 (0.47) | ABL1DHODHFFAR1 | |
| SCHEMBL31704184 | 0.70 | FFAR1 (0.41) | LTB4RLTB4R2FFAR1PPARGPPARD | |
| SCHEMBL21451444 | 0.68 | NPC1 (0.56) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10647710-B2 | Thiazole derivative and applications thereof | MEDSHINE DISCOVERY INC. (CN) | 2020-05-12 | — | — | US | disclosed |
| EP-3566749-A1 | THIAZOLE DERIVATIVE AND APPLICATIONS THEREOF | Medshine Discovery Inc. (CN) | 2019-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10647710-B2 | Thiazole derivative and applications thereof | TSLP, TK2, TK1 | LTB4R 1421/4885LTB4R2 1311/4885ABL1 881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.