Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 12/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21557567 | 0.86 | LTB4R (0.40) | ABL1LTB4RCNR1 | |
| SCHEMBL21557500 | 0.79 | ABL1 (0.42) | ABL1BCRAXLCNR1GSK3B | |
| SCHEMBL21557614 | 0.77 | F2 (0.44) | ABL1BCRAXLGSK3BDYRK1A | |
| SCHEMBL13576751 | 0.76 | GLS (0.46) | — | |
| SCHEMBL15211430 | 0.75 | ESR1 (0.42) | — | |
| SCHEMBL1679129 | 0.74 | MAP3K14 (0.44) | LTB4R | |
| SCHEMBL21557569 | 0.74 | FFAR1 (0.39) | — | |
| SCHEMBL31432485 | 0.74 | MTNR1A (0.47) | LTB4R | |
| SCHEMBL23362454 | 0.72 | GSK3B (0.39) | ABL1LTB4RGSK3BDYRK1A | |
| SCHEMBL21557578 | 0.72 | FAAH (0.54) | ABL1AXLGSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10647710-B2 | Thiazole derivative and applications thereof | MEDSHINE DISCOVERY INC. (CN) | 2020-05-12 | — | — | US | disclosed |
| EP-3566749-A1 | THIAZOLE DERIVATIVE AND APPLICATIONS THEREOF | Medshine Discovery Inc. (CN) | 2019-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10647710-B2 | Thiazole derivative and applications thereof | TSLP, TK2, TK1 | ABL1 881/4885BCR 2894/4885AXL 893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.