Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3626300 | 1.00 | ALDH1A1 (0.33) | ALDH1A1FNTAFNTBOR51E2 | |
| SCHEMBL2151510 | 0.82 | GABRR1 (0.35) | — | |
| SCHEMBL3626326 | 0.78 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL3626324 | 0.78 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL3910421 | 0.74 | FNTA (0.39) | ALDH1A1FNTAFNTBOR51E2 | |
| SCHEMBL3910423 | 0.74 | FNTA (0.39) | ALDH1A1FNTAFNTBOR51E2 | |
| SCHEMBL1961401 | 0.72 | — | — | |
| SCHEMBL1961400 | 0.72 | — | — | |
| SCHEMBL2248126 | 0.69 | — | — | |
| SCHEMBL2250057 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025861-A1 | PROCESS FOR THE PREPARATION OF ( S ) - 3 - CYANO - 5 - METHYLHEXANOIC ACID DERIVATIVES ADN OF PREGABALIN | PFIZER MANUFACTURING IRELAND (IE) | 2012-03-01 | — | — | WO | disclosed |
| US-7781586-B2 | Metathesis catalysts | HOFFMAN-LA ROCHE INC. (US) | 2010-08-24 | — | — | US | disclosed |
| EP-2044095-B1 | NEW RUTHENIUM COMPLEXES AS CATALYSTS FOR METATHESIS REACTIONS | HOFFMANN LA ROCHE (CH) | 2009-08-26 | — | — | EP | disclosed |
| US-20080021219-A1 | Metathesis Catalysts | HOFFMANN-LA ROCHE INC. | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021219-A1 | Metathesis Catalysts | MTX1, MTX2, MLX | ALDH1A1 2087/4885FNTA 2846/4885FNTB 2740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.