Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3626324 | 1.00 | ALDH1A1 (0.36) | ALDH1A1TSHRCYP2C9MEN1KMT2A | |
| SCHEMBL3627866 | 1.00 | ALDH1A1 (0.36) | ALDH1A1TSHRCYP2C9MEN1KMT2A | |
| SCHEMBL3626300 | 0.78 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL21560 | 0.78 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL3027656 | 0.76 | NR1I2 (0.42) | ALDH1A1TSHRMEN1KMT2ATDP1 | |
| SCHEMBL3027654 | 0.76 | NR1I2 (0.42) | ALDH1A1TSHRMEN1KMT2ATDP1 | |
| SCHEMBL16213944 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ATDP1HCAR2 | |
| SCHEMBL8990247 | 0.73 | ALDH1A1 (0.43) | ALDH1A1CYP2C9MEN1KMT2ATDP1 | |
| SCHEMBL11342973 | 0.73 | ALDH1A1 (0.40) | ALDH1A1TSHRCYP2C9MEN1KMT2A | |
| SCHEMBL28912266 | 0.73 | MGAM (0.43) | ALDH1A1TSHRCYP2C9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781586-B2 | Metathesis catalysts | HOFFMAN-LA ROCHE INC. (US) | 2010-08-24 | — | — | US | disclosed |
| EP-2044095-B1 | NEW RUTHENIUM COMPLEXES AS CATALYSTS FOR METATHESIS REACTIONS | HOFFMANN LA ROCHE (CH) | 2009-08-26 | — | — | EP | disclosed |
| EP-2044095-A1 | NEW RUTHENIUM COMPLEXES AS CATALYSTS FOR METAHESIS REACTIONS | F. Hoffmann-Roche AG (CH) | 2009-04-08 | — | — | EP | disclosed |
| US-20080021219-A1 | Metathesis Catalysts | HOFFMANN-LA ROCHE INC. | 2008-01-24 | — | — | US | disclosed |
| WO-2008000644-A1 | NEW RUTHENIUM COMPLEXES AS CATALYSTS FOR METAHESIS REACTIONS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021219-A1 | Metathesis Catalysts | MTX1, MTX2, MLX | ALDH1A1 2087/4885TSHR 2244/4885CYP2C9 788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.