Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | TSPO | P30536 | 1/20 | 0.65 |
| ▸ | GABRA1 | P14867 | 9/20 | 0.62 |
| ▸ | GABRA5 | P31644 | 9/20 | 0.62 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.62 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.62 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.62 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.62 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.62 |
| ▸ | GABRP | O00591 | 2/20 | 0.62 |
| ▸ | GABRD | O14764 | 2/20 | 0.62 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.62 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.62 |
| ▸ | GABRE | P78334 | 2/20 | 0.62 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.62 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.62 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.62 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21562410 | 0.84 | LMNA (0.67) | LMNAGAATSPOGABRA1GABRA5 | |
| SCHEMBL606235 | 0.84 | LMNA (0.70) | LMNAGAATSPOGABRA1GABRA5 | |
| Ro-54864 SCHEMBL29754019 | 0.79 | LMNA (1.00) | LMNAGAATSPOGABRA1GABRA5 | |
| Ro-54864 SCHEMBL60200 | 0.79 | LMNA (1.00) | LMNAGAATSPOGABRA1GABRA5 | |
| SCHEMBL21565184 | 0.78 | LMNA (0.62) | LMNAGAATSPOGABRA1GABRA5 | |
| SCHEMBL10414513 | 0.78 | LMNA (0.74) | LMNAGAATSPOGABRA1GABRA5 | |
| SCHEMBL11613904 | 0.78 | LMNA (0.81) | LMNAGAATSPOGABRA1GABRA5 | |
| Diazepam SCHEMBL1019217 | 0.77 | GABRA1 (1.00) | LMNAGAATSPOGABRA1GABRA5 | |
| Diazepam SCHEMBL29362687 | 0.77 | GABRA1 (1.00) | LMNAGAATSPOGABRA1GABRA5 | |
| Diazepam SCHEMBL21442 | 0.77 | GABRA1 (1.00) | LMNAGAATSPOGABRA1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019215426-A1 | PROCESS FOR FORMING A CARBON-CARBON BOND | THE UNIVERSITY OF MANCHESTER (GB) | 2019-11-14 | — | — | WO | disclosed |