Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2157406 | 0.94 | HTR1A (0.33) | HTR1AACHEKDM4EALDH1A1LMNA | |
| SCHEMBL2156853 | 0.88 | ACHE (0.34) | HTR1AACHE | |
| SCHEMBL2156873 | 0.86 | KDM4E (0.33) | KDM4EALDH1A1LMNATP53GAA | |
| SCHEMBL4394890 | 0.81 | PRKCA (0.34) | HTR1AKDM4EALDH1A1LMNATP53 | |
| SCHEMBL4386985 | 0.79 | DRD2 (0.31) | KDM4EALDH1A1LMNATP53GAA | |
| SCHEMBL2156369 | 0.75 | KDM4E (0.32) | KDM4E | |
| SCHEMBL2156324 | 0.73 | KDM4E (0.36) | KDM4EGAAMAPTTDP1 | |
| SCHEMBL2156557 | 0.73 | PRKCA (0.39) | KDM4EALDH1A1LMNATP53GAA | |
| SCHEMBL4389335 | 0.73 | HRH3 (0.35) | TP53 | |
| SCHEMBL3093288 | 0.72 | PRKCA (0.48) | KDM4EALDH1A1LMNATP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973026-B2 | Thienopyrroles as antiviral agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2011-07-05 | — | — | US | disclosed |