Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.59 |
| ▸ | FAAH | O00519 | 8/20 | 0.57 |
| ▸ | NAAA | Q02083 | 1/20 | 0.56 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12666301 | 0.88 | CASP2 (0.59) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL47703 | 0.88 | CASP2 (0.59) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL12391838 | 0.88 | CASP2 (0.42) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL25878486 | 0.86 | CASP2 (0.57) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL13120985 | 0.86 | CASP2 (0.57) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL12037630 | 0.86 | SLC6A5 (0.54) | CASP2FAAHNAAASLC6A5 | |
| SCHEMBL10088131 | 0.86 | CASP2 (0.56) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL23843180 | 0.85 | CASP2 (0.65) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL1289184 | 0.85 | FAAH (0.71) | CASP2FAAHNAAADNM1EPHX2 | |
| SCHEMBL342717 | 0.85 | FAAH (0.71) | CASP2FAAHNAAADNM1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217682-A1 | CYCLIC CELL-PENETRATING PEPTIDES WITH ONE OR MORE HYDROPHOBIC RESIDUES | OHIO STATE INNOVATION FOUNDATION (US) | 2019-11-14 | — | — | WO | disclosed |