SCHEMBL21563387

SCHEMBL21563387

C=C1C(=O)OC2CC(C)C3CCC(C)C3CC12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.45
▸ RAB9A P51151 3/20 0.45
▸ NPC1 O15118 2/20 0.45
▸ XBP1 P17861 2/20 0.45
▸ HTT P42858 2/20 0.45
▸ MDM2 Q00987 2/20 0.45
▸ PTGS2 P35354 2/20 0.44
▸ PKM P14618 1/20 0.44
▸ RECQL P46063 1/20 0.44
▸ TDP1 Q9NUW8 2/20 0.38
▸ CYP2D6 P10635 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ STAT3 P40763 1/20 0.38
▸ NLRP3 Q96P20 1/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ KDR P35968 1/20 0.38
▸ TERT O14746 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ GLA P06280 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29410309 0.71 MAPT (0.43) MAPTRAB9ANPC1XBP1HTT
SCHEMBL9242953 0.71 MAPT (0.43) MAPTRAB9ANPC1XBP1HTT
SCHEMBL8631899 0.71 MAPT (0.43) MAPTRAB9ANPC1XBP1HTT
SCHEMBL9240777 0.71 MAPT (0.43) MAPTRAB9ANPC1XBP1HTT
SCHEMBL8629540 0.71 MAPT (0.43) MAPTRAB9ANPC1XBP1HTT
SCHEMBL8629536 0.71 MAPT (0.43) MAPTRAB9ANPC1XBP1HTT
SCHEMBL21563384 0.71 CYP19A1 (0.40) MAPTRAB9ANPC1HTTPTGS2
SCHEMBL31238361 0.69 MAPT (0.51) MAPTRAB9ANPC1XBP1HTT
SCHEMBL12620335 0.68 NLRP3 (0.42) MAPTRAB9ANPC1XBP1HTT
Graveolide SCHEMBL31279270 0.66 PTGS2 (0.59) MAPTRAB9ANPC1XBP1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240224882-A1 LIGHT SOURCE SEOUL VIOSYS CO LTD (KR) 2024-07-11 — — US disclosed
US-20240224882-A1 LIGHT SOURCE SEOUL VIOSYS CO LTD (KR) 2024-07-11 — — US disclosed
US-11778953-B2 Light source for plant cultivation SEOUL VIOSYS CO., LTD. (KR) 2023-10-10 — — US disclosed
US-11778953-B2 Light source for plant cultivation SEOUL VIOSYS CO., LTD. (KR) 2023-10-10 — — US disclosed
US-20220192103-A1 LIGHT SOURCE FOR PLANT CULTIVATION SEOUL VIOSYS CO., LTD. (KR) 2022-06-23 — — US disclosed
US-20210332062-A1 HETERO-SUBSTITUTED CYCLIC LACTONE ANALOGUES AND USES THEREOF BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2021-10-28 — — US disclosed
EP-3841869-A1 LIGHT SOURCE FOR PLANT CULTIVATION Seoul Viosys Co., Ltd. (KR) 2021-06-30 — — EP disclosed
US-11021488-B2 Hetero-substituted cyclic lactone analogues and uses thereof BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2021-06-01 — — US disclosed
US-20200060099-A1 LIGHT SOURCE FOR PLANT CULTIVATION SEOUL VIOSYS CO., LTD. (KR) 2020-02-27 — — US disclosed
US-20190345167-A1 HETERO-SUBSTITUTED CYCLIC LACTONE ANALOGUES AND USES THEREOF BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 2019-11-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190345167-A1 HETERO-SUBSTITUTED CYCLIC LACTONE ANALOGUES AND USES THEREOF MCL1, BCL9L, DLD MAPT 4878/4885RAB9A 2722/4885NPC1 4023/4885
US-11021488-B2 Hetero-substituted cyclic lactone analogues and uses thereof MCL1, BCL9L, DLD MAPT 4878/4885RAB9A 2722/4885NPC1 4023/4885
US-20210332062-A1 HETERO-SUBSTITUTED CYCLIC LACTONE ANALOGUES AND USES THEREOF MCL1, BCL9L, DLD MAPT 4878/4885RAB9A 2722/4885NPC1 4023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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