SCHEMBL21564579

SCHEMBL21564579

CC(C)(C)[Si](C)(C)OCCCc1cn(COCC[Si](C)(C)C)c(=O)c(N2CCN(S(C)(=O)=O)CC2)n1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.35
ABL1 P00519 1/20 0.30
BCR P11274 1/20 0.30
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21564766 0.89 DUT (0.39) DUTDGAT1
SCHEMBL21564591 0.88 DUT (0.38) DUTDGAT1
SCHEMBL23258134 0.88 DUT (0.38) DUTDGAT1
SCHEMBL21564587 0.87 DUT (0.38) DUTDGAT1
SCHEMBL21564835 0.86 DUT (0.39) DUTDGAT1
SCHEMBL21552987 0.86 DGAT1 (0.35) ABL1BCRDGAT1
SCHEMBL21552825 0.84 DUT (0.35) DUTDGAT1
SCHEMBL21552907 0.84
SCHEMBL21552949 0.83 ALDH1A1 (0.36) DUT
SCHEMBL26031610 0.83 DUT (0.35) DUTDGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250090-A1 KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE IMAGO BIOSCIENCES INC (US) 2023-08-10 US disclosed
US-20230250090-A1 KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE IMAGO BIOSCIENCES INC (US) 2023-08-10 US disclosed
US-11578059-B2 KDM1A inhibitors for the treatment of disease Imago Biosciences. Inc. (US) 2023-02-14 US disclosed
US-20210115023-A1 KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE IMAGO BIOSCIENCES, INC. 2021-04-22 US disclosed
WO-2019217972-A1 KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE IMAGO BIOSCIENCES, INC. (US) 2019-11-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250090-A1 KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE KDM1B, KDM1A, KDM2A DUT 613/4885ABL1 160/4885BCR 236/4885
US-20210115023-A1 KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE KDM1A, KDM1B, KDM2A DUT 581/4885ABL1 148/4885BCR 253/4885
US-11578059-B2 KDM1A inhibitors for the treatment of disease KDM1B, KDM1A, KDM2A DUT 613/4885ABL1 160/4885BCR 236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.