SCHEMBL21552949

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21564531	0.90	ALDH1A1 (0.38)	ALDH1A1GBA1OPRM1OPRD1OGFRL1
	SCHEMBL21564766	0.86	DUT (0.39)	DUT
	SCHEMBL23258134	0.86	DUT (0.38)	DUT
	SCHEMBL21564591	0.86	DUT (0.38)	DUT
	SCHEMBL21564532	0.85	OPRM1 (0.35)	ALDH1A1GBA1OPRM1OPRD1OGFRL1
	SCHEMBL21564587	0.85	DUT (0.38)	DUT
	SCHEMBL26031610	0.84	DUT (0.35)	DUT
	SCHEMBL21564835	0.84	DUT (0.39)	DUT
	SCHEMBL21564579	0.83	DUT (0.35)	DUT
	SCHEMBL21552998	0.83	DGAT1 (0.35)	ALDH1A1OPRM1OPRD1OGFRL1DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.