Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 5/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1433039 | 0.88 | OPRK1 (0.38) | NR1D1NR1H3OPRK1HPGDTSHR | |
| SCHEMBL26035583 | 0.87 | CA12 (0.40) | NR1D1NR1H3CA12CA1CA7 | |
| SCHEMBL23711054 | 0.84 | CA12 (0.36) | NR1D1NR1H3OPRK1TSHRCA12 | |
| SCHEMBL26035581 | 0.83 | ALOX15 (0.33) | NR1D1NR1H3TSHRCA12CA1 | |
| SCHEMBL10170339 | 0.82 | TSHR (0.36) | OPRK1HPGDTSHRRAB9AL3MBTL1 | |
| SCHEMBL27420033 | 0.81 | NR1D1 (0.38) | NR1D1NR1H3CA12CA1CA7 | |
| SCHEMBL7567960 | 0.81 | CHRM2 (0.37) | NR1D1NR1H3OPRK1TSHRCA12 | |
| SCHEMBL2137303 | 0.81 | TDP1 (0.38) | NR1D1NR1H3OPRK1TSHRCA12 | |
| SCHEMBL4335588 | 0.79 | HIF1A (0.35) | NR1D1NR1H3OPRK1HPGDTSHR | |
| SCHEMBL16087987 | 0.79 | NR1D1 (0.32) | NR1D1NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019214546-A1 | FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 (CN) | 2019-11-14 | — | — | WO | disclosed |