Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NR1D1 | P20393 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3031948 | 0.90 | ALOX15 (0.41) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL1758843 | 0.90 | ALOX15 (0.41) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL8412132 | 0.87 | ALOX15 (0.42) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL4335588 | 0.85 | HIF1A (0.35) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL26035583 | 0.85 | CA12 (0.40) | NR1D1NR1H3CA14CA12CA1 | |
| SCHEMBL19952793 | 0.84 | TDP1 (0.45) | ALOX15KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL21566414 | 0.83 | NR1D1 (0.33) | NR1D1TSHRNR1H3CA14CA12 | |
| SCHEMBL30678011 | 0.82 | CA14 (0.31) | NR1D1CA14 | |
| SCHEMBL16087987 | 0.81 | NR1D1 (0.32) | NR1D1NR1H3 | |
| SCHEMBL15548847 | 0.80 | NR1D1 (0.36) | TDP1NR1D1CYP2D6NR1H3CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731960-B2 | Biheterocyclic compound | Sumitomo Pharma Co., Ltd. (JP) | 2023-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731960-B2 | Biheterocyclic compound | NR4A3, NGF, OGFR | ALOX15 924/4885KDM4E 1008/4885MAPT 4598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.