Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 14/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 14/20 | 0.45 |
| ▸ | POLA1 | P09884 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29292359 | 0.90 | NR1H2 (0.43) | NR1H2NR1H3POLA1PDE4D | |
| SCHEMBL29295648 | 0.86 | NR1H2 (0.35) | NR1H2NR1H3POLA1LMNACYP3A4 | |
| SCHEMBL29295646 | 0.85 | NR1H2 (0.50) | NR1H2NR1H3POLA1PDE4D | |
| SCHEMBL29296723 | 0.84 | NR1H2 (0.43) | NR1H2NR1H3POLA1PDE4D | |
| SCHEMBL29295337 | 0.83 | NR1H2 (0.49) | NR1H2NR1H3POLA1PDE4D | |
| SCHEMBL29292380 | 0.81 | NR1H2 (0.42) | NR1H2NR1H3POLA1PDE4D | |
| SCHEMBL29295347 | 0.81 | NR1H2 (0.61) | NR1H2NR1H3POLA1 | |
| SCHEMBL21552202 | 0.81 | NR1H2 (0.61) | NR1H2NR1H3POLA1 | |
| SCHEMBL29295655 | 0.79 | RAB9A (0.37) | NR1H2NR1H3POLA1CYP3A4 | |
| SCHEMBL29292374 | 0.79 | RAB9A (0.37) | NR1H2NR1H3POLA1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217591-A1 | ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2019-11-14 | — | — | WO | disclosed |