Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.66 |
| ▸ | RORC | P51449 | 15/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5372049 | 0.88 | HTR6 (0.85) | HTR6RORCDRD2SLC6A4SCN9A | |
| Oxalic Acid SCHEMBL5379663 | 0.85 | HTR6 (0.78) | HTR6RORCDRD2SLC6A4SCN9A | |
| SCHEMBL5383569 | 0.84 | HTR6 (0.79) | HTR6RORCDRD2SLC6A4SCN9A | |
| SCHEMBL5767852 | 0.78 | HTR6 (0.72) | HTR6DRD2SLC6A4 | |
| SCHEMBL5371232 | 0.77 | HTR6 (0.71) | HTR6DRD2 | |
| Hydrochloric Acid SCHEMBL5371228 | 0.77 | HTR6 (0.70) | HTR6DRD2 | |
| SCHEMBL5771470 | 0.77 | HTR6 (0.70) | HTR6RORCDRD2 | |
| SCHEMBL5770874 | 0.77 | HTR6 (0.70) | HTR6DRD2SLC6A4 | |
| Oxalic Acid SCHEMBL5375349 | 0.76 | HTR6 (0.66) | HTR6DRD2SLC6A4 | |
| Oxalic Acid SCHEMBL6649675 | 0.76 | HTR6 (0.63) | HTR6RORCDRD2SLC6A4SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10478436-B2 | Application of 5-HT6 receptor antagonists for the alleviation of cognitive deficits of down syndrome | THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2019-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10478436-B2 | Application of 5-HT6 receptor antagonists for the alleviation of cognitive deficits of down syndrome | HTR6, HTR7, HTR5A | HTR6 1/4885RORC 4675/4885DRD2 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.