Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21076020 | 0.90 | PPARG (0.38) | EPHX2PPARGPPARATP53TSHR | |
| SCHEMBL21574736 | 0.80 | IDO1 (0.39) | EPHX2PPARGPPARANPC1RAB9A | |
| SCHEMBL21075947 | 0.73 | TAAR1 (0.45) | PPARGPPARAKMT2ANPC1RAB9A | |
| SCHEMBL18856419 | 0.73 | TP53 (0.35) | TP53TSHR | |
| SCHEMBL22726316 | 0.71 | CYP3A4 (0.40) | HRH3CYP3A4MEN1KMT2ACYP1A2 | |
| SCHEMBL21538822 | 0.71 | PPARA (0.51) | EPHX2PPARGPPARA | |
| SCHEMBL18856359 | 0.70 | UBE2M (0.35) | PPARALMNAMAPTTP53 | |
| SCHEMBL7435082 | 0.69 | TAAR1 (0.46) | KMT2ANPC1RAB9ATAAR1ALDH1A1 | |
| SCHEMBL13850028 | 0.68 | PPARG (0.42) | EPHX2PPARGPPARATAAR1ALDH1A1 | |
| SCHEMBL14402394 | 0.68 | PPARG (0.42) | EPHX2PPARGPPARATAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057421-B1 | ALKYL LINKED QUINOLINYL MODULATORS OF ROR(GAMMA)T | JANSSEN PHARMACEUTICA NV (BE) | 2019-11-20 | — | — | EP | disclosed |