SCHEMBL2157377

SCHEMBL2157377

CCN(CC(N)=O)c1ccc(N)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.64
TSHR P16473 4/20 0.64
L3MBTL1 Q9Y468 3/20 0.64
MAPK1 P28482 3/20 0.64
GFER P55789 2/20 0.64
CYP3A4 P08684 2/20 0.64
TDP1 Q9NUW8 2/20 0.64
PSMD14 O00487 1/20 0.64
RECQL P46063 1/20 0.64
ESRRG P62508 1/20 0.47
MAPT P10636 6/20 0.43
HPGD P15428 3/20 0.43
GAA P10253 2/20 0.43
KDM4E B2RXH2 1/20 0.43
GLA P06280 1/20 0.43
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
POLB P06746 2/20 0.42
ALDH3A1 P30838 1/20 0.41
ALDH1A3 P47895 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10796721 0.98 ALDH1A1 (0.62) ALDH1A1TSHRL3MBTL1MAPK1GFER
Acetamide SCHEMBL10826366 0.85 ALDH1A1 (0.76) ALDH1A1TSHRL3MBTL1MAPK1GFER
SCHEMBL3141234 0.83 MEN1 (0.50) ALDH1A1TSHRL3MBTL1MAPK1GFER
SCHEMBL25894216 0.82 ALDH1A1 (0.60) ALDH1A1TSHRL3MBTL1MAPK1GFER
SCHEMBL13644994 0.81 TDP1 (0.44) ALDH1A1TSHRL3MBTL1MAPK1GFER
Oxalic Acid SCHEMBL3517831 0.81 ALDH1A1 (0.76) ALDH1A1TSHRL3MBTL1MAPK1GFER
SCHEMBL8467252 0.80 ALDH1A1 (1.00) ALDH1A1TSHRL3MBTL1MAPK1GFER
SCHEMBL33781 0.80 ALDH1A1 (1.00) ALDH1A1TSHRL3MBTL1MAPK1GFER
SCHEMBL2157459 0.78 S100B (0.70) ALDH1A1TSHRL3MBTL1MAPK1GFER
SCHEMBL8695005 0.78 ALDH1A1 (0.70) ALDH1A1TSHRL3MBTL1MAPK1GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6540791-B1 Oxidizer, a buffer of borates and/or alkalizing agents, a stabilizer, and a hair care ingredient such as surfactant, catalyst (enzyme), thickener, or conditioner; shelf life, bleaching performance THE PROCTER & GAMBLE COMPANY 2003-04-01 US claimed
EP-0459900-B2 Process for dyeing of keratinic fibres with 2,4-diamino-1,3-dimethoxybenzene in an acid medium and composition using this process OREAL (FR) 2002-08-28 EP claimed
WO-2001072271-A2 STABLE ALKALINE HAIR BLEACHING AND COLORING COMPOSITIONS AND METHOD FOR USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2001-10-04 WO claimed
WO-2001072272-A2 STABLE ALKALINE HAIR BLEACHING COMPOSITIONS AND METHOD FOR USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2001-10-04 WO claimed
US-5900028-A Oxidation dye composition for keratin fibres comprising 2-amino-3-hydroxypyridine and a P-phenylenediamine or P-aminophenol oxidation base, and dyeing process L 'OREAL (FR) 1999-05-04 US claimed
US-5735909-A Compositions and processes for the oxidation dyeing of keratin fibres with an oxidation base, a meta-aminophenol coupler, and a 6-hydroxyindoline coupler L'OREAL (FR) 1998-04-07 US claimed
EP-0766958-B1 Oxidation dyeing composition for keratinous fibers comprising 2-amino-3-hydroxypyridine and an oxidation base and dyeing process OREAL (FR) 1997-11-19 EP claimed
EP-0605320-B1 Dye composition for keratinic fibres based on paraphenylenediamine, metaphenylenediamines and benzimidazol derivates, and the dyeing process using same OREAL (FR) 1997-04-09 EP claimed
EP-0728465-B1 Composition for dyeing keratinous fibers comprising a meta-aminophenol and 6-hydroxyindoline, and dyeing process using such a composition OREAL (FR) 1997-03-19 EP claimed
US-5578087-A Dyeing compositions for keratinous fibres based on para-phenylene-diamines, meta-phenylenediamine and benzimidazole derivatives, and dyeing process employing them L'OREAL (FR) 1996-11-26 US claimed
US-5073174-A Hair, two stage, deep warm colors L'OREAL (FR) 1991-12-17 US claimed
EP-0295474-B1 CHLOROMETAPHENYLENEDIAMINES, THEIR USE AS COUPLING AGENTS IN OXYDATION COLOURING OF KERATINIC FIBRES, COLOURITY COMPOSITIONS FOR HAIR CONTAINING THESE COMPOUNDS AND COLOURING PROCESS USING THESE COMPOSITIONS L'OREAL (FR) 1991-07-17 EP claimed
US-4985042-A New substituted metaaminophenols, a process for their preparation, hair-dyeing compositions containing them and a hair-dyeing process L'OREAL (FR) 1991-01-15 US claimed
US-4954131-A Substituted metaaminophenols, a process for their preparation, hair-dyeing compositions containing them and a hair-dyeing process L'OREAL (FR) 1990-09-04 US claimed
US-4865619-A Use, as a coupler, of 2,4-diamino-1,3-dimethoxybenzene or one of its salts, in combination with oxidation dye precursors, for dyeing human hair, hair dyeing composition containing the said coupler and process for preparing the said coupler L'OREAL (FR) 1989-09-12 US claimed
US-4865618-A New chloro-meta-phenylenediamines, their use as couplers in the oxidation dyeing of keratinous fibres, dyeing compositions for hair containing these compounds and dyeing process using the said L'OREAL (FR) 1989-09-12 US claimed
US-4863480-A OXIDATION COLOR DYES THE FRENCH JOINT STOCK COMPANY "L'OREAL" (FR) 1989-09-05 US claimed
US-4692166-A OXIDATION COLOR DYES USED WITH DIAMINOBENZENES OR AMINO PHENOLS; MINIMIZATION OF RED HUE L'OREAL (FR) 1987-09-08 US claimed
US-4324553-A OXIDATION COLOR DYES L'OREAL (FR) 1982-04-13 US claimed
US-4323360-A Dyeing compositions for hair which contain 2,4-diamino-butoxybenzene and/or a salt thereof as the coupling agent L'OREAL (FR) 1982-04-06 US claimed