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SCHEMBL21574063

SCHEMBL21574063

COc1c(C(=O)N(C(C)=O)c2c(Br)cc(C(C)(C(C)(F)F)C(F)(F)F)cc2OC(F)F)cccc1N(C)C(=O)c1ccncc1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ GPBAR1 Q8TDU6 19/20 0.36
▸ MLYCD O95822 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16150431 0.92 GPBAR1 (0.37) GPBAR1MLYCD
SCHEMBL21574048 0.85 GPBAR1 (0.36) GPBAR1MLYCD
SCHEMBL22332377 0.84 GPBAR1 (0.38) GPBAR1MLYCD
SCHEMBL23026190 0.77 GPBAR1 (0.37) GPBAR1MLYCD
SCHEMBL16150671 0.77 GPBAR1 (0.38) GPBAR1MLYCD
SCHEMBL29376079 0.77 GPBAR1 (0.38) GPBAR1MLYCD
SCHEMBL14844565 0.76 GPBAR1 (0.42) GPBAR1MLYCD
SCHEMBL16868757 0.74 GPBAR1 (0.36) GPBAR1MLYCD
SCHEMBL17829477 0.72 MLYCD (0.37) GPBAR1MLYCD
SCHEMBL21574072 0.72 RXFP1 (0.33) GPBAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3087053-B1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2019-11-20 — — EP disclosed