Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17897032 | 0.83 | MGLL (0.46) | KMT2AACLYTSHR | |
| SCHEMBL4832334 | 0.80 | SMN1; SMN2 (0.43) | KDM4EKMT2APTGS2SYKACLY | |
| SCHEMBL10428803 | 0.74 | KMT2A (0.57) | KMT2AMMP1MMP9MMP8LMNA | |
| SCHEMBL22701125 | 0.73 | NQO1 (0.36) | KDM4EALDH1A1HSD17B10MAPTCYP1A2 | |
| SCHEMBL14012356 | 0.73 | ALDH1A1 (0.46) | KDM4EKMT2ALMNAALDH1A1MAPT | |
| SCHEMBL20607419 | 0.72 | KMT2A (0.47) | KDM4EKMT2AMMP1MMP9MMP8 | |
| SCHEMBL15517469 | 0.71 | LMNA (0.53) | KDM4EKMT2APTGS2MMP1MMP9 | |
| SCHEMBL13104128 | 0.71 | LMNA (0.53) | KDM4EKMT2ALMNAALDH1A1HSD17B10 | |
| SCHEMBL257259 | 0.70 | MEP1B (0.38) | KDM4EALDH1A1 | |
| SCHEMBL29463962 | 0.70 | MEP1B (0.38) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3569229-A1 | PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR DISEASES ASSOCIATED WITH AMPA RECEPTORS | Public University Corporation Yokohama City University (JP) | 2019-11-20 | — | — | EP | disclosed |