Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.65 |
| ▸ | ATM | Q13315 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | TYMS | P04818 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | AHR | P35869 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29907833 | 0.79 | MAPK1 (1.00) | MAPK1ATMKDM4ETYMSALDH1A1 | |
| SCHEMBL13309034 | 0.79 | MAPK1 (1.00) | MAPK1ATMKDM4ETYMSALDH1A1 | |
| SCHEMBL18159667 | 0.79 | MAPK1 (0.54) | MAPK1ATMKDM4ETYMSALDH1A1 | |
| SCHEMBL24254039 | 0.77 | MAPK1 (0.96) | MAPK1ATMKDM4ETYMSALDH1A1 | |
| SCHEMBL20151723 | 0.77 | ALDH1A1 (0.61) | MAPK1ATMKDM4ETYMSALDH1A1 | |
| SCHEMBL24254100 | 0.77 | MAPK1 (0.87) | MAPK1ATMKDM4ETYMSALDH1A1 | |
| SCHEMBL24782411 | 0.76 | MAPK1 (0.51) | MAPK1ATMKDM4ETYMSALDH1A1 | |
| SCHEMBL24823907 | 0.76 | MAPK1 (0.64) | MAPK1ATMKDM4ETYMSALDH1A1 | |
| SCHEMBL12172735 | 0.75 | MAPK1 (0.68) | MAPK1ATMKDM4ETYMSALDH1A1 | |
| SCHEMBL17069551 | 0.74 | MAPK1 (0.60) | MAPK1ATMKDM4ETYMSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190355908-A1 | Organic Cocrystal and Applications of the Same | HU WENPING (CN) | 2019-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190355908-A1 | Organic Cocrystal and Applications of the Same | OTC, SOD1, AOC1 | MAPK1 3390/4885ATM 1649/4885KDM4E 2308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.