SCHEMBL21579352

SCHEMBL21579352

C=Cc1cccc(B(O)OC)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ENPP2 Q13822 4/20 0.40
TRPA1 O75762 1/20 0.40
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
PTGS2 P35354 1/20 0.35
TTR P02766 1/20 0.34
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
RELA Q04206 3/20 0.33
CYP26B1 Q9NR63 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
ABL1 P00519 1/20 0.31
BCR P11274 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL397161 0.79 ENPP2 (0.55) TP53TDP1ENPP2ALDH1A1TSHR
SCHEMBL29155126 0.77 ENPP2 (0.53) TP53TDP1ENPP2ALDH1A1TSHR
SCHEMBL11686471 0.77 ALDH1A1 (0.46) TDP1ENPP2TRPA1ALDH1A1TSHR
SCHEMBL29155031 0.77 ENPP2 (0.53) TP53TDP1ENPP2ALDH1A1TSHR
SCHEMBL20273151 0.75 ENPP2 (0.59) ENPP2ALDH1A1CA1CA2
SCHEMBL1711771 0.73 ENPP2 (0.59) TDP1ENPP2ALDH1A1TSHRCYP3A4
SCHEMBL8297905 0.73 ACHE (0.44) TP53ENPP2ALDH1A1RELACA1
SCHEMBL16136505 0.72 ENPP2 (0.41) ENPP2ALDH1A1TSHRMAPTCA1
SCHEMBL22960487 0.72 ENPP2 (0.41) ENPP2ALDH1A1CYP2D6CYP2C19CA1
SCHEMBL16247947 0.72 ENPP2 (0.46) ENPP2ALDH1A1PTGS2RELACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190352459-A1 Chemical Compounds For Coating Of Nanostructures SPAGO NANOMEDICAL AB (SE) 2019-11-21 US disclosed