Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 6/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20273151 | 0.79 | ENPP2 (0.59) | ENPP2CA1CA2KDM4EALDH1A1 | |
| SCHEMBL8297905 | 0.78 | ACHE (0.44) | ENPP2IDO1CA1CA2ALDH1A1 | |
| SCHEMBL1711771 | 0.78 | ENPP2 (0.59) | ENPP2CA1CA2ALDH1A1CA5A | |
| SCHEMBL25559690 | 0.77 | ENPP2 (0.40) | ENPP2APPIDO1KDM4EALDH1A1 | |
| SCHEMBL787196 | 0.76 | ENPP2 (0.56) | ENPP2CA1CA2KDM4EALDH1A1 | |
| SCHEMBL16136505 | 0.76 | ENPP2 (0.41) | ENPP2IDO1CA1CA2ALDH1A1 | |
| SCHEMBL29582240 | 0.76 | ENPP2 (0.46) | ENPP2CA1CA2KDM4EALDH1A1 | |
| SCHEMBL16247947 | 0.76 | ENPP2 (0.46) | ENPP2CA1CA2KDM4EALDH1A1 | |
| SCHEMBL5182053 | 0.76 | ALDH1A1 (0.61) | ENPP2CA1CA2KDM4EALDH1A1 | |
| SCHEMBL19820142 | 0.76 | ENPP2 (0.41) | ENPP2ALDH1A1EGFRORAI1ORAI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040079-A1 | 10H-phenothiazine ferroptosis inhibitor as well as the preparative method and the use thereof | Chengdu Henghao Investment Co. Limited (CN) | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040079-A1 | 10H-phenothiazine ferroptosis inhibitor as well as the preparative method and the use thereof | AIFM2, FECH, GPX4 | ENPP2 3907/4885APP 479/4885IDO1 1626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.