Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20349764 | 0.85 | PSENEN (0.36) | PSENENCASP1CTSSCTSK | |
| SCHEMBL24992769 | 0.85 | — | — | |
| SCHEMBL19401583 | 0.85 | PSENEN (0.36) | PSENENCASP1CTSSCTSK | |
| SCHEMBL10067158 | 0.84 | CYP2C9 (0.41) | CYP2C9CTSSCTSK | |
| SCHEMBL18462936 | 0.84 | CYP2C9 (0.41) | CYP2C9CTSSCTSK | |
| SCHEMBL18462935 | 0.84 | CYP2C9 (0.43) | CYP2C9 | |
| SCHEMBL22139575 | 0.81 | PSENEN (0.38) | PSENENCTSSCTSK | |
| SCHEMBL19776873 | 0.81 | CYP2C9 (0.38) | CYP2C9 | |
| SCHEMBL17860258 | 0.81 | CYP2C9 (0.38) | CYP2C9 | |
| SCHEMBL19776047 | 0.80 | CASP1 (0.39) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190351066-A1 | PRODRUGS OF CYTOTOXIC ACTIVE AGENTS HAVING ENZYMATICALLY CLEAVABLE GROUPS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190351066-A1 | PRODRUGS OF CYTOTOXIC ACTIVE AGENTS HAVING ENZYMATICALLY CLEAVABLE GROUPS | LGMN, BUB1B, KIF15 | PSENEN 1531/4885CYP2C9 4556/4885CASP1 910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.