Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28687188 | 0.81 | NPC1 (0.37) | NPC1ALDH1A1KDM4EHSD17B10NPSR1 | |
| SCHEMBL21580196 | 0.79 | NPC1 (0.35) | NPC1ALDH1A1KDM4EHSD17B10NPSR1 | |
| SCHEMBL23625193 | 0.76 | OPRK1 (0.38) | NPC1ALDH1A1KDM4EHSD17B10NPSR1 | |
| SCHEMBL21580199 | 0.76 | KDM4E (0.38) | NPC1ALDH1A1KDM4ENPSR1POLB | |
| SCHEMBL21580202 | 0.76 | ADORA2B (0.35) | NPC1ALDH1A1KDM4EHSD17B10POLB | |
| SCHEMBL156075 | 0.76 | TRPA1 (0.50) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL17696721 | 0.76 | TRPA1 (0.50) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL17696719 | 0.76 | TRPA1 (0.50) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL17696718 | 0.76 | TRPA1 (0.50) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL17696722 | 0.76 | TRPA1 (0.50) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204122-B | 2-Furyl-and 2-thienyl-substituted dihydropyran and tetrahydropyran as aromatic chemicals | 巴斯夫欧洲公司 | 2025-01-07 | — | — | CN | disclosed |
| EP-3802758-B1 | 2-FURYL- AND 2-THIENYL-SUBSTITUTED DI- AND TETRAHYDROPYRANS FOR USE AS AROMA CHEMICALS | BASF SE (DE) | 2024-12-04 | — | — | EP | disclosed |
| US-11993760-B2 | 2-furyl- and 2-thienyl-substituted di- and tetrahydropyrans for use as aroma chemicals | BASF SE (DE) | 2024-05-28 | — | — | US | disclosed |
| US-20210207057-A1 | 2-FURYL- AND 2-THIENYL-SUBSTITUTED DI- AND TETRAHYDROPYRANS FOR USE AS AROMA CHEMICALS | BASF SE (DE) | 2021-07-08 | — | — | US | disclosed |
| US-20210207057-A1 | 2-FURYL- AND 2-THIENYL-SUBSTITUTED DI- AND TETRAHYDROPYRANS FOR USE AS AROMA CHEMICALS | BASF SE (DE) | 2021-07-08 | — | — | US | disclosed |
| EP-3802758-A1 | 2-FURYL- AND 2-THIENYL-SUBSTITUTED DI- AND TETRAHYDROPYRANS FOR USE AS AROMA CHEMICALS | BASF SE (DE) | 2021-04-14 | — | — | EP | disclosed |
| CN-112204122-A | 2-furyl-and 2-thienyl-substituted dihydropyrans and tetrahydropyrans as fragrance chemicals | 巴斯夫欧洲公司 | 2021-01-08 | — | — | CN | disclosed |
| WO-2019224373-A1 | 2-FURYL- AND 2-THIENYL-SUBSTITUTED DI- AND TETRAHYDROPYRANS FOR USE AS AROMA CHEMICALS | BASF SE (DE) | 2019-11-28 | — | — | WO | disclosed |
| WO-2019224373-A1 | 2-FURYL- AND 2-THIENYL-SUBSTITUTED DI- AND TETRAHYDROPYRANS FOR USE AS AROMA CHEMICALS | BASF SE (DE) | 2019-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210207057-A1 | 2-FURYL- AND 2-THIENYL-SUBSTITUTED DI- AND TETRAHYDROPYRANS FOR USE AS AROMA CHEMICALS | TRPA1, TAS2R5, TAS2R3 | NPC1 4154/4885ALDH1A1 72/4885KDM4E 1940/4885 |
| US-11993760-B2 | 2-furyl- and 2-thienyl-substituted di- and tetrahydropyrans for use as aroma chemicals | TRPA1, TAS2R5, TAS2R3 | NPC1 4154/4885ALDH1A1 72/4885KDM4E 1940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.