SCHEMBL2158174

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2157436	0.84	ABCB1 (0.48)	DRD3ADRA1AOPRM1SLC6A3CACNA1F
	SCHEMBL2157385	0.83	MEN1 (0.51)	TRPV1ADRA1AADRA1DADRA1BLMNA
	SCHEMBL24893038	0.83	TRPV1 (0.61)	TRPV1DRD3ADRA1AOPRM1SLC6A3
	SCHEMBL7032760	0.82	LMNA (0.56)	DRD3ADRA1AOPRM1SLC6A3LMNA
	SCHEMBL7030072	0.82	DRD3 (0.63)	DRD3ADRA1AOPRM1SLC6A3CACNA1F
	SCHEMBL7032807	0.82	DRD3 (0.53)	DRD3ADRA1AOPRM1SLC6A3CACNA1F
	Hydrochloric Acid SCHEMBL2157325	0.82	CYP3A4 (0.56)	DRD3ADRA1AOPRM1SLC6A3LMNA
	Hydrochloric Acid SCHEMBL2157444	0.81	DRD3 (0.61)	DRD3ADRA1AOPRM1SLC6A3CACNA1F
	Hydrochloric Acid SCHEMBL2158183	0.81	DRD3 (0.52)	DRD3ADRA1AOPRM1SLC6A3CACNA1F
	SCHEMBL1333961	0.81	KCNH2 (0.54)	ADRA1AADRA1DADRA1BLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.