Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13751142 | 0.84 | ALDH1A1 (0.39) | ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL13751280 | 0.79 | ALDH1A1 (0.37) | ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL13751271 | 0.76 | ALDH1A1 (0.35) | ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL19120709 | 0.76 | DRD2 (0.36) | ALDH1A1MEN1LMNACYP1A2ADRB2 | |
| SCHEMBL8442604 | 0.76 | LMNA (0.36) | MEN1LMNACYP1A2ADRB2THRB | |
| SCHEMBL10942894 | 0.76 | LMNA (0.36) | MEN1LMNACYP1A2ADRB2THRB | |
| SCHEMBL28494816 | 0.76 | LMNA (0.36) | MEN1LMNACYP1A2ADRB2THRB | |
| SCHEMBL19276040 | 0.74 | OPRM1 (0.37) | MEN1LMNACYP1A2ADRB2THRB | |
| SCHEMBL7897923 | 0.72 | — | — | |
| SCHEMBL172898 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975058-B2 | Imidazolyl kinase inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-04-13 | — | — | US | disclosed |
| US-20190367487-A1 | IMIDAZOLYL KINASE INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190367487-A1 | IMIDAZOLYL KINASE INHIBITORS AND USES THEREOF | PRKACB, PRKACG, PRKACA | ALDH1A1 3176/4885MEN1 2299/4885LMNA 2180/4885 |
| US-10975058-B2 | Imidazolyl kinase inhibitors and uses thereof | PRKACB, PRKACG, PRKACA | ALDH1A1 3176/4885MEN1 2299/4885LMNA 2180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.