Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | GPR34 | Q9UPC5 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | RRM1 | P23921 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21583890 | 0.86 | SIGMAR1 (0.52) | SIGMAR1BCHEMAOBSLC2A1MEN1 | |
| SCHEMBL23929172 | 0.86 | SIGMAR1 (0.52) | SIGMAR1BCHEMAOBSLC2A1MEN1 | |
| SCHEMBL30211156 | 0.79 | PDK1 (0.50) | SIGMAR1BCHEMAOBMEN1KMT2A | |
| SCHEMBL23958491 | 0.79 | PDK1 (0.50) | SIGMAR1BCHEMAOBMEN1KMT2A | |
| SCHEMBL28969319 | 0.79 | PDK1 (0.50) | SIGMAR1BCHEMAOBMEN1KMT2A | |
| SCHEMBL21583955 | 0.78 | TAAR1 (0.50) | SIGMAR1BCHEMAOBMAOA | |
| SCHEMBL23632922 | 0.78 | ADRA1A (0.49) | SIGMAR1BCHESLC2A1MEN1KMT2A | |
| SCHEMBL28976177 | 0.78 | ADRA1A (0.49) | SIGMAR1BCHESLC2A1MEN1KMT2A | |
| SCHEMBL29762300 | 0.78 | ADRA1A (0.49) | SIGMAR1BCHESLC2A1MEN1KMT2A | |
| SCHEMBL21583966 | 0.77 | BCHE (0.51) | BCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019228443-A1 | SELECTIVE ESTROGEN RECEPTOR DOWNREGULATORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2019-12-05 | — | — | WO | disclosed |