SCHEMBL2158581

SCHEMBL2158581

CCCCOc1c(CCCC)cccc1COC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 3/20 0.41
BID P55957 3/20 0.40
MCL1 Q07820 3/20 0.40
PPARG P37231 3/20 0.40
BCL2L1 Q07817 2/20 0.40
BAK1 Q16611 2/20 0.40
KAT8 Q9H7Z6 2/20 0.40
EP300 Q09472 1/20 0.40
KAT2A Q92830 1/20 0.40
KAT2B Q92831 1/20 0.40
KAT5 Q92993 1/20 0.40
SAE1 Q9UBE0 1/20 0.40
PTGES O14684 1/20 0.40
ALOX5 P09917 1/20 0.40
LTB4R Q15722 1/20 0.40
LTB4R2 Q9NPC1 1/20 0.40
TSHR P16473 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
MAPK1 P28482 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL975210 0.79 PTPN11 (0.46) PPARABIDMCL1PPARGBCL2L1
SCHEMBL28793611 0.78 PTPN11 (0.45) PPARABIDMCL1PPARGBCL2L1
SCHEMBL976080 0.78 PTPN11 (0.45) PPARABIDMCL1PPARGBCL2L1
SCHEMBL974446 0.78 PTPN11 (0.45) PPARABIDMCL1PPARGBCL2L1
SCHEMBL975211 0.78 PTPN11 (0.45) PPARABIDMCL1PPARGBCL2L1
SCHEMBL2158760 0.77 GABRA1 (0.38) PPARGTSHRL3MBTL1ALDH1A1LMNA
SCHEMBL515984 0.77 ALOX5 (0.42) PPARABIDMCL1PPARGBCL2L1
SCHEMBL14974812 0.76 TSHR (0.53) TSHRTDP1L3MBTL1MAPK1ALDH1A1
SCHEMBL28882638 0.76 LTB4R (0.42) PPARAPPARGPTGESALOX5LTB4R
SCHEMBL368881 0.74 BID (0.50) PPARABIDMCL1PPARGBCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2550313-B1 METHOD OF MAKING POLYCARBONATE SABIC INNOVATIVE PLASTICS IP (NL) 2014-04-23 EP disclosed
EP-2550313-A1 METHOD OF MAKING POLYCARBONATE SABIC Innovative Plastics IP B.V. (NL) 2013-01-30 EP disclosed
WO-2011117774-A1 METHOD OF MAKING POLYCARBONATE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-09-29 WO disclosed
US-7985824-B1 Method of making polycarbonate SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-07-26 US disclosed